"Three times I appealed to the LORD about this, that it would leave me, but he said to me, 'My grace is sufficient for you, for power is made perfect in weakness.'"
(2 Corinthians 12:8-9)
It doesn't make sense. The first will be last and the last first. If you want to gain your life you must lose it. And power is made perfect in weakness. It doesn't make sense. At least not in "the real world." Then again, it's not supposed to. It's Kingdom Language! It's how God works (and wants us to live, too).
We like to think God is with us most powerfully when all is going smoothly. Yet how often are we truly focused on God when all is going smoothly? But when we go through difficult times, God is almost always on our heart! Maybe that's part of the reason why God reminded Paul (2 Cor. 12) that when we are at our weak, God is strong! God is able to do amazing work in our lives when we're at our weakest points.
(It kinda makes you want to ask for weakness, doesn't it?)